Pollution by chemical substances such as POPs (Persistent Organic Pollutants), EDCs (Endocrine Disrupting Chemicals) and PBTs (Persistent Bio-accumulative and Toxic substances) in the ecosystem has become more complex and varied, increasing the possibility of irreversible damage to human health or the ecosystem. Even at this moment, such chemical substances are continuously developed, manufactured and circulated, and accordingly the type and quantity of chemical substances flowing into the ecosystem are also increasing. There are 100,000 or more chemical substances circulated around the world, and about 38,000 chemical substances are used in Korea. It has been reported that 2,000 or more new substances are developed and commercialized around the world and about 300 new chemical substances are introduced to Korean market each year. Furthermore, the circulation and production of such chemical substances is also continuously increasing around the world, and the introduction of and the support for environment-friendly chemical substances management policy have become the major issue of the international society. Therefore it is necessary to have a management priority setting system for various chemical substances is required for efficient management.